Description

Methyl (16Alpha,17Beta)-17-Hydroxyyohimban-16-Carboxylate is a high-purity, specialized indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel alkaloid-based therapeutics.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding activity and structure-activity relationships (SAR) within the yohimbine alkaloid family.
• Process Chemistry: Serves as a precursor in the scale-up and optimization of manufacturing processes for complex organic molecules.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and the exploration of new medicinal compounds.

Basic Information

Product Name	Methyl (16Alpha,17Beta)-17-Hydroxyyohimban-16-Carboxylate
CAS No.	549-84-8
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Methyl 16α,17β-Dihydroxy-16-carboxyyohimban-16-carboxylate; 16α-Carbomethoxy-17β-hydroxyyohimban; Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17β)-; Methyl 17β-hydroxy-16α-yohimban-16α-carboxylate; 549-84-8; Methyl (16α,17β)-17-hydroxyyohimban-16-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl (16Alpha,17Beta)-17-Hydroxyyohimban-16-Carboxylate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.