Description

Phenadoxone Hydrochloride is a synthetic opioid compound of significant interest in pharmaceutical research and development. This substance serves as a crucial intermediate and reference standard for analytical and pharmacological studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and analgesic research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of specialized opioid-based analgesic compounds for research purposes.
• Reference Standard: Certified material for quality control (QC) and quality assurance (QA) in analytical laboratories, ensuring method validation and regulatory compliance.
• Pharmacological Research: Used in preclinical studies to investigate opioid receptor interactions, analgesic efficacy, and structure-activity relationships (SAR).
• Forensic Analysis: Serves as an analytical standard for the identification and quantification of substances in forensic toxicology and law enforcement laboratories.
• Academic & Clinical Studies: Supports academic research and clinical trials focused on pain management and central nervous system (CNS) drug development.

Basic Information

Product Name	Phenadoxone Hydrochloride
CAS No.	545-91-5
Molecular Formula	C₂₄H₃₁NO₂·HCl
Molecular Weight	401.97 g/mol
Synonyms	Phenadoxone HCl; 6-Morpholino-4,4-diphenylheptan-3-one hydrochloride; Heptazone hydrochloride; CB-11; NIH 7525; Morphinan-6-one, 4,4-diphenyl-6-morpholino-, hydrochloride; 4,4-Diphenyl-6-morpholinoheptan-3-one hydrochloride
EINECS	Contact for details

Quality Control

Our Phenadoxone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.