Description

(S)-1-Bromo-2-Methylbutane is a high-purity chiral alkyl halide building block essential for advanced organic synthesis. This compound is valued for its role in introducing the (S)-2-methylbutyl moiety, enabling the stereoselective construction of complex molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop enantiomerically pure active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.
• Material Science: Potential monomer or modifier for creating polymers with tailored chiral properties.

Basic Information

Product Name	(S)-1-Bromo-2-Methylbutane
CAS No.	534-00-9
Molecular Formula	C5H11Br
Molecular Weight	151.05 g/mol
Synonyms	(S)-(-)-1-Bromo-2-methylbutane; (S)-2-Methylbutyl bromide; (S)-sec-Butylmethyl bromide; (S)-1-Bromo-2-methylbutane; (-)-(S)-1-Bromo-2-methylbutane; (S)-α-Methylbutyl bromide; 1-Bromo-2-methylbutane, (S)-; (2S)-1-Bromo-2-methylbutane
EINECS	208-580-8

Quality Control

Our (S)-1-Bromo-2-Methylbutane is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. Our standard grade meets the rigorous demands of research and process development, with specifications tailored to support cGMP manufacturing where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at 2-8°C or as specified on the label. Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and allowed to reach ambient temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]D20	-5.0° to -7.0° (c=1 in CHCl3)
Density (20°C)	1.22 - 1.25 g/mL
Refractive Index nD20	1.448 - 1.452
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.