Description

4-Methylesculetin is a naturally occurring coumarin derivative, also known as 4-Methylumbelliferone. This versatile organic compound serves as a critical intermediate and reference standard in advanced chemical synthesis and analytical research. It is primarily sought after by the pharmaceutical, life sciences, and fine chemical industries for its role in developing active pharmaceutical ingredients (APIs), biochemical probes, and as a key building block for more complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive coumarin derivatives and complex drug molecules.
• Biochemical Research: Used as a reference standard and substrate in enzymatic assays and metabolic pathway studies.
• Fluorescent Probe Development: Serves as a core structure for creating fluorescent dyes and sensors used in cell biology and diagnostics.
• Fine Chemical Synthesis: An important building block for synthesizing fragrances, agrochemicals, and other specialty organic compounds.
• Analytical Chemistry: Employed as a high-purity standard for HPLC, LC-MS, and other chromatographic methods to ensure analytical accuracy.

Basic Information

Product Name	4-Methylesculetin
CAS No.	529-84-0
Molecular Formula	C10H8O4
Molecular Weight	192.17 g/mol
Synonyms	4-Methylumbelliferone; 4-Methyl-7-hydroxycoumarin; 7-Hydroxy-4-methylcoumarin; 4-Methyl-7-hydroxy-2H-1-benzopyran-2-one; Hymecromone; β-Methylumbelliferone; 4-MU; 4-Methyl-7-oxycoumarin
EINECS	208-463-2

Quality Control

Our 4-Methylesculetin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	290°C - 295°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.