Description

n-Hydroxyphthalimide is a versatile and highly functionalized organic compound, serving as a critical intermediate in advanced chemical synthesis. Its primary value lies in its role as a precursor for the synthesis of N-alkoxyphthalimides, which are powerful and selective oxidizing agents used in organic transformations. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it enables the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring selective oxidation steps.
• Organic Synthesis Reagent: Used as a precursor to generate N-oxy radicals for the selective oxidation of hydrocarbons and other organic substrates under mild conditions.
• Agrochemical Production: Intermediate in the manufacture of advanced pesticides and herbicides, contributing to improved efficacy and selectivity.
• Polymer Chemistry: Employed in the synthesis of functional polymers and as a modifier to introduce specific chemical functionalities into polymer chains.
• Catalyst Ligand Synthesis: Serves as a starting material for creating specialized ligands used in homogeneous catalysis.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new oxidation methodologies and reaction pathways.

Basic Information

Product Name	n-Hydroxyphthalimide
CAS No.	524-38-9
Molecular Formula	C8H5NO3
Molecular Weight	163.13 g/mol
Synonyms	1-Hydroxyphthalimide; N-Hydroxyphthalimide; 1-Hydroxy-1H-isoindole-1,3(2H)-dione; NHPI; HPI; Phthalimide, N-hydroxy-; N-Hydroxy-1,3-dioxoisoindoline; 1,3-Dioxoisoindolin-1-ol
EINECS	208-361-7

Quality Control

Our n-Hydroxyphthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	230 - 235 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.