Description

[S-(R*,R*)]-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Hydroxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Phthalide is a high-purity, complex heterocyclic compound of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and a key intermediate for the research and development of novel pharmaceutical agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential alkaloid-derived therapeutics and central nervous system (CNS) active compounds.
• Asymmetric Synthesis: Utilized as a sophisticated building block in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as an intermediate for producing specialty chemicals with specific chiral configurations.
• Academic & Institutional Research: Applied in chemical biology and synthetic methodology development within university and institutional laboratories.

Basic Information

Product Name	[S-(R*,R*)]-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Hydroxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Phthalide
CAS No.	521-40-4
Molecular Formula	C22H23NO7
Molecular Weight	413.42 g/mol
Synonyms	(-)-Bicuculline; (R)-Bicuculline; Bicuculline; NSC 22445; L-Bicuculline; 6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-isobenzofuranone; (S)-Bicuculline; 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, (S)-
EINECS	208-317-6

Quality Control

Our [S-(R*,R*)]-6,7-Dimethoxy-3-(5,6,7,8-Tetrahydro-4-Hydroxy-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Yl)Phthalide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.