Description

(9α,13α,14α)-5,6-Didehydro-4-Hydroxy-3,6-Dimethoxy-17-Methylmorphinan-7-One is a high-purity pharmaceutical intermediate of significant importance in the synthesis of specialized active pharmaceutical ingredients (APIs). Its complex morphinan structure makes it a critical building block for advanced medicinal chemistry research and development. This compound is essential for manufacturers and research institutions focused on developing and producing controlled analgesic and antitussive agents, requiring a reliable supply of high-quality, precisely characterized chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent opioid analgesics and related therapeutic agents.
• Analgesic API Synthesis: Used in the research and development of new pain management medications, leveraging its core morphinan scaffold.
• Antitussive Drug Development: Serves as a starting material for compounds targeting severe cough suppression.
• Medicinal Chemistry Research: Provides a versatile template for structure-activity relationship (SAR) studies and the creation of novel chemical entities in neuropharmacology.
• Reference Standard: Can be utilized as an analytical standard in quality control laboratories for method development and impurity profiling.
• Controlled Substance Synthesis: Employed under strict regulatory oversight for the licensed production of specific scheduled pharmaceuticals.

Basic Information

Product Name	(9α,13α,14α)-5,6-Didehydro-4-Hydroxy-3,6-Dimethoxy-17-Methylmorphinan-7-One
CAS No.	510-42-9
Molecular Formula	C₁₉H₂₃NO₄
Molecular Weight	329.39 g/mol
Synonyms	4,5α-Epoxy-3-hydroxy-17-methyl-6-methoxy-α,17-dimethyl-α-(2-propenyl)-6,14-ethenomorphinan-7-methanol; 4,5α-Epoxy-17-methyl-3,6α-dihydroxy-α,17-dimethyl-α-(2-propenyl)-6,14-ethenomorphinan-7-methanol; 7,8-Didehydro-4,5α-epoxy-17-methyl-3,6α-dihydroxy-α,17-dimethyl-α-(2-propenyl)-6,14-ethenomorphinan; Dihydroetorphine Impurity; Etorphine related compound A
EINECS	Contact for details

Quality Control

Our (9α,13α,14α)-5,6-Didehydro-4-Hydroxy-3,6-Dimethoxy-17-Methylmorphinan-7-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting specifications for pharmaceutical R&D use. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.