Description

5,5-Diphenylhydantoin is a white to off-white crystalline powder belonging to the hydantoin class of organic compounds. It serves as a crucial intermediate and reference standard in the research and development of pharmaceuticals, particularly in the field of anticonvulsant and antiarrhythmic agents. This high-purity compound is essential for analytical laboratories, R&D facilities, and manufacturers in the pharmaceutical and fine chemical industries seeking a reliable and well-characterized material for synthesis, method development, and quality control.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced pharmaceutical compounds and active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), gas chromatography (GC), and other analytical methods for identification, assay, and impurity profiling.
• Biochemical Research: Employed in pharmacological and metabolic studies related to sodium channel function and neurological activity.
• Chemical Synthesis: Acts as a versatile precursor for the preparation of more complex heterocyclic compounds and derivatives in organic chemistry.
• Quality Control & Validation: Essential for calibrating instruments and validating analytical methods in GMP and ISO-compliant laboratory environments.

Basic Information

Product Name	5,5-Diphenylhydantoin
CAS No.	57-41-0
Molecular Formula	C15H12N2O2
Molecular Weight	252.27 g/mol
Synonyms	Phenytoin; Diphenylhydantoin; 5,5-Diphenyl-2,4-imidazolidinedione; Dilantin (trade name); 5,5-DPH; Antisacer; Difenin; Epanutin; Fenitoina
EINECS	200-329-6

Quality Control

Our 5,5-Diphenylhydantoin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications and test results. We can supply material that meets various pharmacopeial standards, including USP and EP, upon request. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and analytical science.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.