Description

1,2-Ethanediyl Bismethanethiosulfonate is a specialized organosulfur compound with the CAS number 55-95-8, primarily recognized as a versatile cross-linking and modifying agent. Its value lies in its ability to form stable disulfide bonds, making it a critical reagent for introducing specific functional groups or creating controlled molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, polymer science, and advanced materials sectors who require precise chemical modification and conjugation capabilities.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly where disulfide linkages are required for stability or targeted drug release.
• Bioconjugation Reagent: Facilitates the site-specific cross-linking of peptides, proteins, and antibodies for diagnostic assays, antibody-drug conjugates (ADCs), and biomaterial engineering.
• Polymer Modification: Acts as a cross-linker or chain extender in the production of specialty polymers, elastomers, and resins to enhance thermal stability and mechanical properties.
• Surface Functionalization: Employed to modify the surface chemistry of nanoparticles, gold surfaces, and other materials to impart specific chemical reactivity or biocompatibility.
• Chemical Synthesis: Serves as a key building block in organic synthesis for constructing complex sulfur-containing heterocycles and other advanced molecular structures.
• Research & Development: A valuable tool in chemical biology and materials science R&D for studying disulfide bond formation and developing new functional materials.

Basic Information

Product Name	1,2-Ethanediyl Bismethanethiosulfonate
CAS No.	55-95-8
Molecular Formula	C4H8O4S4
Molecular Weight	248.36 g/mol
Synonyms	Ethylene bis(methanethiosulfonate); Ethylene dimethanesulfonothioate; 1,2-Bis(methanesulfonylthio)ethane; Bis(methanesulfonothioylthio)ethane; DTME (Dithiobismaleimidoethane) related precursor; Methanethiosulfonic acid, 1,2-ethanediyl ester; Disulfide cross-linker reagent; EMS-Ethylene
EINECS	200-247-8

Quality Control

Our 1,2-Ethanediyl Bismethanethiosulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under inert atmosphere when appropriate to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.