Description

1-(3,5-Dimethylphenyl)-6,7-Dihydro-1H-Indazol-4(5H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the indazolone class of heterocyclic compounds. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable and consistent supply of complex building blocks for medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Employed in multi-step organic synthesis to construct more complex molecular architectures with potential biological activity.
• Reference Standard: Acts as a high-purity analytical standard for quality control, method development, and regulatory submissions in pharmaceutical manufacturing.
• Biochemical Research: Utilized in biochemical assays to study enzyme inhibition, receptor binding, and other pharmacological mechanisms.

Basic Information

Product Name	1-(3,5-Dimethylphenyl)-6,7-Dihydro-1H-Indazol-4(5H)-One
CAS No.	499206-28-9
Molecular Formula	C15H16N2O
Molecular Weight	240.30 g/mol
Synonyms	1-(3,5-Dimethylphenyl)-4,5,6,7-tetrahydro-1H-indazol-4-one; 6,7-Dihydro-1-(3,5-dimethylphenyl)-1H-indazol-4(5H)-one; 4,5,6,7-Tetrahydro-1-(3,5-dimethylphenyl)-1H-indazol-4-one; 1-(3,5-Dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-one; 499206-28-9; 1H-Indazol-4(5H)-one, 6,7-dihydro-1-(3,5-dimethylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(3,5-Dimethylphenyl)-6,7-Dihydro-1H-Indazol-4(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and the stringent requirements of global research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.