Description

2-[(3,3-Dimethyl-2-Oxobutyl)Sulfanyl]-3-(4-Ethoxyphenyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a sophisticated heterocyclic organic compound featuring a fused benzothienopyrimidinone core, which serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its complex molecular architecture, incorporating specific sulfanyl and ethoxyphenyl functionalities, makes it a valuable building block for developing novel therapeutic agents with targeted biological activity. This high-purity intermediate is essential for research and development chemists and manufacturers in the pharmaceutical industry, particularly those focused on kinase inhibitors and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Kinase Inhibitor Development: Serves as a core scaffold or building block for the synthesis of potential protein kinase inhibitors due to its privileged benzothieno[2,3-d]pyrimidinone structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Employed in the development of chemical probes for studying specific biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-complexity intermediates.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis methodology and new therapeutic modality exploration.

Basic Information

Item	Details
Product Name	2-[(3,3-Dimethyl-2-Oxobutyl)Sulfanyl]-3-(4-Ethoxyphenyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	499125-29-0
Molecular Formula	C24H26N2O3S2
Molecular Weight	454.60 g/mol
Synonyms	3-(4-Ethoxyphenyl)-2-[(3,3-dimethyl-2-oxobutyl)thio]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 2-((3,3-Dimethyl-2-oxobutyl)thio)-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; Benzothienopyrimidinone derivative; 499125-29-0; 2-[(3,3-Dimethyl-2-oxobutyl)sulfanyl]-3-(4-ethoxyphenyl)-5,6,7,8-tetrahydro-[1]benzothieno[2,3-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our production of 2-[(3,3-Dimethyl-2-Oxobutyl)Sulfanyl]-3-(4-Ethoxyphenyl)-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for pharmaceutical applications. All materials are subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure and to prevent contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.