Description

4,7-Ethano-1H-Indene-8,9-Diol, 2,3,3A,4,7,7A-Hexahydro-2,2,4-Trimethyl-, (3As,4S,7R,7Ar,8S,9R)- (9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure with multiple chiral centers makes it a valuable building block for the development of novel, high-value chemical entities. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring complex polycyclic frameworks.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereospecific pesticides and herbicides where its unique structure can impart specific biological targeting.
• Advanced Material Research: Serves as a precursor for specialty polymers or liquid crystals that require rigid, chiral molecular components.
• Catalyst Ligand Development: Potential use as a backbone for designing novel chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic & Institutional Research: A valuable compound for methodological studies in synthetic organic chemistry and stereochemistry.

Basic Information

Product Name	4,7-Ethano-1H-Indene-8,9-Diol, 2,3,3A,4,7,7A-Hexahydro-2,2,4-Trimethyl-, (3As,4S,7R,7Ar,8S,9R)- (9Ci)
CAS No.	499121-61-8
Molecular Formula	C14H22O2
Molecular Weight	222.32 g/mol
Synonyms	(3aR,4S,7R,7aS,8S,9R)-2,2,4-Trimethyl-2,3,3a,4,7,7a-hexahydro-4,7-ethano-1H-indene-8,9-diol; (3aR,4S,7R,7aS,8S,9R)-2,2,4-Trimethyl-2,3,3a,4,7,7a-hexahydro-4,7-etheno-1H-indene-8,9-diol; Hexahydro-2,2,4-trimethyl-4,7-ethano-1H-indene-8,9-diol, (3aR,4S,7R,7aS,8S,9R)-rel-; Chiral Hexahydro Trimethyl Ethano Indene Diol; 4,7-Ethano-1H-indene-8,9-diol, 2,3,3a,4,7,7a-hexahydro-2,2,4-trimethyl-, (3aR,4S,7R,7aS,8S,9R)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.