Description

2-Bromo-4-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzyl Alcohol
CAS No.	497959-33-8
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	α-(Bromomethyl)-2-bromo-α,α,α-trifluoro-p-toluene; [2-Bromo-4-(trifluoromethyl)phenyl]methanol; 2-Bromo-α,α,α-trifluoro-p-tolylcarbinol; (2-Bromo-4-trifluoromethylphenyl)methanol; 2-Bromo-4-(trifluoromethyl)benzenemethanol; Benzyl alcohol, 2-bromo-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 2-Bromo-4-(Trifluoromethyl)Benzyl Alcohol is monitored through in-process controls and final batch analysis using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.