Description

4-Formyl-5-(Trifluoromethyl)-1-Methyl-1H-Pyrazole is a high-value, multi-functional heterocyclic building block characterized by its reactive formyl group and trifluoromethyl substituent. This compound is essential for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique structure imparts desirable metabolic stability and bioavailability. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a building block for creating functional polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Formyl-5-(Trifluoromethyl)-1-Methyl-1H-Pyrazole
CAS No.	497833-04-2
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	1-Methyl-4-formyl-5-(trifluoromethyl)-1H-pyrazole; 5-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxaldehyde; 1-Methyl-5-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde; 4-Pyrazolecarboxaldehyde, 5-(trifluoromethyl)-1-methyl-; 5-(Trifluoromethyl)-1-methylpyrazole-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Formyl-5-(Trifluoromethyl)-1-Methyl-1H-Pyrazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) with HPLC purity, NMR, and mass spectrometry confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.