Description

8-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key synthetic intermediate, enabling the construction of complex molecular architectures for research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Organic Synthesis Building Block: Used in the construction of fused polycyclic systems and other sophisticated heterocycles in academic and industrial laboratories.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a component for creating organic electronic materials or specialty polymers with unique properties.

Basic Information

Product Name	8-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
CAS No.	497261-38-8
Molecular Formula	C11H11BrN2
Molecular Weight	251.12 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 8-Bromo-2,3,4,5-tetrahydro-1H-β-carboline; 8-Bromotetrahydro-β-carboline; 8-Bromo-1,2,3,4-tetrahydro-β-carboline; 8-Bromo-THBC; 497261-38-8; 8-Bromo-9H-pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.