Description

Methyl 2-({[(Cyclopropylcarbonyl)Amino]Carbonothioyl}Amino)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates, especially within medicinal chemistry programs targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, particularly those with benzothiophene cores.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients in pre-clinical and early clinical stages.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for investigating enzyme function or cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Methyl 2-({[(Cyclopropylcarbonyl)Amino]Carbonothioyl}Amino)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate
CAS No.	497091-50-6
Molecular Formula	C15H17N3O3S2
Molecular Weight	351.44 g/mol
Synonyms	Methyl 2-({[(cyclopropylcarbonyl)amino]carbonothioyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-({[(Cyclopropylcarbonyl)Amino]Carbonothioyl}Amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester; 497091-50-6; Cyclopropanecarboxylic acid N-[(3-methoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamothioyl]amide; Methyl 2-[[(cyclopropanecarbonylamino)carbothioyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.