Description

Bicyclo[2.1.1]Hexane-1-Methanol, 4-Bromo- (9Ci) is a high-purity, specialized bicyclic organic building block. This compound is valued for its unique strained ring structure and functional handles, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by R&D and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand synthesis, and the development of novel materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its bicyclic scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers and specialty chemicals with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and cross-coupling reactions.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane-1-Methanol, 4-Bromo- (9Ci)
CAS No.	497074-22-3
Molecular Formula	C8H11BrO
Molecular Weight	203.08 g/mol
Synonyms	4-Bromobicyclo[2.1.1]hexane-1-methanol; 4-Bromo-1-(hydroxymethyl)bicyclo[2.1.1]hexane; (4-Bromobicyclo[2.1.1]hex-1-yl)methanol; Bicyclo[2.1.1]hexane-1-methanol, 4-bromo-; 1-(Hydroxymethyl)-4-bromobicyclo[2.1.1]hexane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane-1-Methanol, 4-Bromo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency essential for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.