Description

Acetamide, n-[(3Ar,7Ar)-2,3,3A,4,7,7A-Hexahydro-6-Methyl-1,3-Dioxo-1H-Isoindol-4-Yl]-, Rel- (9Ci) is a specialized organic compound featuring a complex isoindole-derived structure. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides or fungicides with novel modes of action.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or probes used in mechanistic studies.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined stereochemistry (Rel-), enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers with specific thermal or optical properties.

Basic Information

Item	Details
Product Name	Acetamide, n-[(3Ar,7Ar)-2,3,3A,4,7,7A-Hexahydro-6-Methyl-1,3-Dioxo-1H-Isoindol-4-Yl]-, Rel- (9Ci)
CAS No.	496953-87-8
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	rel-N-[(3aR,7aR)-2,3,3a,4,7,7a-Hexahydro-6-methyl-1,3-dioxo-1H-isoindol-4-yl]acetamide; (3aR,7aR)-4-Acetamido-6-methyl-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindole; 4-Acetamido-6-methyl-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindole (rel-); Acetamide, N-[(3aR,7aR)-hexahydro-6-methyl-1,3-dioxo-1H-isoindol-4-yl]-, rel-; CAS 496953-87-8
EINECS	Contact for details

Quality Control

Our Acetamide, n-[(3Ar,7Ar)-2,3,3A,4,7,7A-Hexahydro-6-Methyl-1,3-Dioxo-1H-Isoindol-4-Yl]-, Rel- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is accompanied by a detailed Certificate of Analysis (COA) available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.