Description

5-(Bromoacetyl)Thiophene-2-Carbonitrile is a versatile and highly functionalized heterocyclic building block. This compound is valued for its reactive bromoacetyl and nitrile groups, which enable its use in complex organic synthesis and pharmaceutical research. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its thiophene core for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its conjugated thiophene system.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Heterocyclic Chemistry: Employed in the construction of complex, polycyclic heteroaromatic systems for various chemical applications.
• Chemical Biology Probes: Used to create molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5-(Bromoacetyl)Thiophene-2-Carbonitrile
CAS No.	496879-84-6
Molecular Formula	C7H4BrNOS
Molecular Weight	230.08 g/mol
Synonyms	2-Cyano-5-bromoacetylthiophene; 5-Bromoacetyl-2-cyanothiophene; 2-Thiophenecarbonitrile, 5-(bromoacetyl)-; 5-(2-Bromoacetyl)thiophene-2-carbonitrile; Bromoacetylthiophenecarbonitrile; 5-Bromoacetylthiophene-2-carbonitrile; (5-Cyano-2-thienyl)-2-bromoethanone
EINECS	Contact for details

Quality Control

Our 5-(Bromoacetyl)Thiophene-2-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.