Description

Benzene, 4-(1,1-Dimethylethyl)-1,2-Diiodo- is a specialized diiodinated aromatic compound, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic placement of iodine atoms, which act as excellent leaving groups for cross-coupling reactions, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for coupling reactions like Suzuki-Miyaura or Ullmann-type couplings.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the tert-butyl and iodine groups allow for structural diversification.
• Ligand & Catalyst Development: Serves as a starting material for creating sophisticated ligands and organocatalysts used in asymmetric synthesis and material science.
• Advanced Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring specific aromatic backbones.
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and tags due to the reactivity of the iodine atoms for bioconjugation strategies.
• Custom & Contract Manufacturing: A critical raw material for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.

Basic Information

Product Name	Benzene, 4-(1,1-Dimethylethyl)-1,2-Diiodo-
CAS No.	496800-71-6
Molecular Formula	C10H12I2
Molecular Weight	370.01 g/mol
Synonyms	1,2-Diiodo-4-tert-butylbenzene; 4-tert-Butyl-1,2-diiodobenzene; p-tert-Butyl-o-diiodobenzene; 1,2-Diiodo-4-(tert-butyl)benzene; 4-(1,1-Dimethylethyl)-1,2-diiodobenzene; 4-tert-Butylbenzene-1,2-diyl diiodide
EINECS	Contact for details

Quality Control

Our production of Benzene, 4-(1,1-Dimethylethyl)-1,2-Diiodo- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and elemental analysis, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance with global regulatory frameworks, and custom synthesis to meet specific client specifications (e.g., >98%, >99% purity) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and organic iodine content, the container should be kept in a secondary containment and away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.