Description

1-[(5-Bromothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block featuring a bromothiophene and a piperidine carboxylic acid scaffold. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), serving as a key intermediate in the synthesis of complex molecules. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate its unique sulfonamide-linked bicyclic structure.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates targeting a range of therapeutic areas, including central nervous system (CNS) disorders and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromine and carboxylic acid functional groups.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides that leverage the thiophene moiety.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or organic electronic materials where the conjugated thiophene system is beneficial.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Item	Details
Product Name	1-[(5-Bromothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid
CAS No.	496778-03-1
Molecular Formula	C10H12BrNO4S2
Molecular Weight	354.24 g/mol
Synonyms	1-[(5-Bromothiophen-2-yl)sulfonyl]piperidine-3-carboxylic acid; 3-Carboxy-1-(5-bromo-2-thienylsulfonyl)piperidine; 1-(5-Bromothiophene-2-sulfonyl)piperidine-3-carboxylic acid; Piperidine-3-carboxylic acid, 1-[(5-bromo-2-thienyl)sulfonyl]-; 5-Bromo-2-(3-carboxypiperidin-1-ylsulfonyl)thiophene
EINECS	Contact for details

Quality Control

Our 1-[(5-Bromothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.