Description

1,3-Dihydro-2,1-Benzisothiazol-5-Amine 2,2-Dioxide is a high-purity, specialized heterocyclic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique benzisothiazole dioxide core structure makes it a valuable intermediate for developing novel compounds with targeted biological and material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, dyes, and advanced organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing complex heterocyclic systems and sulfonamide derivatives in academic and industrial R&D.
• Bioconjugation & Probe Development: The amine functionality allows for conjugation, making it useful in creating fluorescent probes or biochemical tools for diagnostic applications.

Basic Information

Product Name	1,3-Dihydro-2,1-Benzisothiazol-5-Amine 2,2-Dioxide
CAS No.	496055-43-7
Molecular Formula	C7H8N2O2S
Molecular Weight	184.21 g/mol
Synonyms	5-Amino-1,2-benzisothiazole 1,1-Dioxide; 5-Amino-2,1-benzisothiazol-3(2H)-one 1,1-Dioxide; 2,1-Benzisothiazol-5-amine, 1,1-dioxide, 1,3-dihydro-; 1,3-Dihydro-2,1-benzisothiazol-5-amine 1,1-dioxide; 5-Amino-1,2-benzisothiazole-3(2H)-one 1,1-Dioxide; 5-Aminobenzisothiazole dioxide; 496055-43-7
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-2,1-Benzisothiazol-5-Amine 2,2-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.