Description

Ethyl 2-(2-(2-((4-Amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamido)thiazol-4-yl)acetate is a sophisticated heterocyclic building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate, enabling the construction of complex molecular architectures with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fused thienopyrimidine-thiazole core.
• Biochemical Tool Compound: Potential utility in developing probes for studying specific enzymatic pathways or cellular processes in academic and industrial research settings.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a complex, functionalized heterocyclic scaffold.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of active pharmaceutical ingredients (APIs).
• Preclinical Development: Used to produce compounds for pharmacological profiling, toxicology studies, and formulation development.

Basic Information

Product Name	Ethyl 2-(2-(2-((4-Amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamido)thiazol-4-yl)acetate
CAS No.	496028-84-3
Molecular Formula	C21H23N5O3S2
Molecular Weight	465.57 g/mol
Synonyms	Ethyl {2-[2-({2-[(4-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetyl}amino)-1,3-thiazol-4-yl]}acetate; 4H-Cyclohepta[4,5]thieno[2,3-d]pyrimidine-2-thiol, 4-amino-5,6,7,8-tetrahydro-, 2-acetate deriv.; 496028-84-3; [2-[2-[[2-(4-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanylacetyl]amino]-1,3-thiazol-4-yl]acetic acid ethyl ester; A high-purity pharmaceutical intermediate based on tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine.
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-(2-((4-Amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamido)thiazol-4-yl)acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.