Description

3-Benzyl-5-Fluoro-1H-Indole is a high-purity, fluorinated indole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a benzyl group and a fluorine atom on the indole scaffold, makes it a valuable intermediate for creating novel compounds with targeted biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functional component in the synthesis of specialty polymers and organic electronic materials.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fluorine Chemistry: An important substrate for further fluorination or functionalization reactions to create more complex fluorinated molecules.

Basic Information

Product Name	3-Benzyl-5-Fluoro-1H-Indole
CAS No.	494780-29-9
Molecular Formula	C15H12FN
Molecular Weight	225.26 g/mol
Synonyms	5-Fluoro-3-benzyl-1H-indole; 3-Benzyl-5-fluoroindole; 1H-Indole, 3-benzyl-5-fluoro-; 5-Fluoro-3-benzylindole; 494780-29-9; 3-(Phenylmethyl)-5-fluoro-1H-indole
EINECS	Contact for details

Quality Control

Every batch of 3-Benzyl-5-Fluoro-1H-Indole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.