Description

(4-Hydroxymethylthiazol-2-Yl)Carbamic Acid tert-Butyl Ester is a high-purity, protected thiazole derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing thiazole heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the thiazole moiety imparts specific biological activity.
• Chemical Biology & Proteomics: Serves as a building block for creating specialized probes, inhibitors, or linkers in biochemical research.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced materials.
• Academic & Contract Research: Employed in methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	(4-Hydroxymethylthiazol-2-Yl)Carbamic Acid tert-Butyl Ester
CAS No.	494769-44-7
Molecular Formula	C10H16N2O3S
Molecular Weight	244.31 g/mol
Synonyms	tert-Butyl N-(4-(hydroxymethyl)-1,3-thiazol-2-yl)carbamate; 2-(((tert-Butoxycarbonyl)amino)-4-(hydroxymethyl)thiazole; Boc-4-Hydroxymethylthiazol-2-ylamine; (4-Hydroxymethyl-2-thiazolyl)carbamic acid tert-butyl ester; N-Boc-2-amino-4-hydroxymethylthiazole; 2-((tert-Butoxycarbonyl)amino)-4-(hydroxymethyl)thiazole; 2-Amino-4-hydroxymethylthiazole N-Boc derivative
EINECS	Contact for details

Quality Control

Our (4-Hydroxymethylthiazol-2-Yl)Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.