Description

5,8-Indolizinedione,Hexahydro-,(8As)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS number 494225-07-9. This compound is valued for its complex indolizinedione core structure, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research and development organizations and production facilities in the pharmaceutical and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds with potential biological activity.
• Organic Synthesis Research: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.
• Academic & Contract Research: Serves as a valuable reagent for investigating new synthetic methodologies and reaction pathways in university and CRO laboratories.

Basic Information

Product Name	5,8-Indolizinedione,Hexahydro-,(8As)-(9Ci)
CAS No.	494225-07-9
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Hexahydro-5,8-indolizinedione; (8aS)-Octahydro-5,8-indolizinedione; 5,8-Indolizinedione, hexahydro-, (8aS)-; 494225-07-9; (8aS)-5,8-Dioxohexahydroindolizine; (8aS)-Octahydroindolizine-5,8-dione
EINECS	Contact for details

Quality Control

Our 5,8-Indolizinedione,Hexahydro-,(8As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.