Description

5-(4-Bromo-Phenyl)-4-Methyl-4 H-[1,2,4]Triazole-3-Thiol is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, incorporating both a reactive thiol group and a halogenated aromatic ring, making it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly those targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, especially for kinase inhibitors and other enzyme-targeted therapies.
• Agrochemical Synthesis: Used in the creation of new fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands in coordination chemistry and catalysis due to its sulfur and nitrogen donor atoms.
• Material Science Research: Employed in the synthesis of functional polymers or organic electronic materials where the triazole-thiol moiety can impart specific properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	5-(4-Bromo-Phenyl)-4-Methyl-4 H-[1,2,4]Triazole-3-Thiol
CAS No.	494194-50-2
Molecular Formula	C9H8BrN3S
Molecular Weight	270.15 g/mol
Synonyms	4-Methyl-5-(4-bromophenyl)-4H-1,2,4-triazole-3-thiol; 5-(4-Bromophenyl)-4-methyl-1,2,4-triazole-3-thiol; 5-(p-Bromophenyl)-4-methyl-4H-1,2,4-triazole-3-thiol; 4-Methyl-5-(4-bromophenyl)-1,2,4-triazole-3-thiol; 3-Mercapto-4-methyl-5-(4-bromophenyl)-1,2,4-triazole; 494194-50-2
EINECS	Contact for details

Quality Control

Our 5-(4-Bromo-Phenyl)-4-Methyl-4 H-[1,2,4]Triazole-3-Thiol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided to maintain purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.