Description

2-Phenyl-5-(Trifluoromethyl)-1H-Indole is a high-value, multi-functional indole derivative distinguished by its unique phenyl and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic synthesis building block, enabling the development of novel compounds with enhanced properties. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology, CNS disorders, and anti-inflammatory applications.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core structure or dopant in the development of advanced electroluminescent materials.
• Ligand and Catalyst Development: Serves as a scaffold for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Fluorescent Probe Synthesis: Utilized in the design of molecular probes and sensors for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and material science research.

Basic Information

Product Name	2-Phenyl-5-(Trifluoromethyl)-1H-Indole
CAS No.	491601-38-8
Molecular Formula	C15H10F3N
Molecular Weight	261.24 g/mol
Synonyms	5-(Trifluoromethyl)-2-phenyl-1H-indole; 2-Phenyl-5-(trifluoromethyl)indole; 1H-Indole, 2-phenyl-5-(trifluoromethyl)-; 2-Phenyl-5-trifluoromethylindole; 5-Trifluoromethyl-2-phenylindole; 491601-38-8; 2-Phenyl-5-trifluoromethyl-1H-indole
EINECS	Contact for details

Quality Control

Every batch of 2-Phenyl-5-(Trifluoromethyl)-1H-Indole is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.