Description

1H-Indole-3-Carbonitrile, 2-Iodo-1-Methyl- CAS NO 490039-77-5 is a specialized halogenated indole derivative, a high-value building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for developing novel active compounds. It is primarily sought after by the pharmaceutical, agrochemical, and advanced materials industries for applications in drug discovery, crop protection, and functional material research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds for potential therapeutic agents, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the indole core for biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of organic semiconductors, conductive polymers, and photoactive materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical studies due to its reactive iodine and nitrile functional groups.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry, particularly in cross-coupling and cyclization reactions.

Basic Information

Item	Details
Product Name	1H-Indole-3-Carbonitrile, 2-Iodo-1-Methyl-
CAS No.	490039-77-5
Molecular Formula	C10H7IN2
Molecular Weight	282.08 g/mol
Synonyms	2-Iodo-1-methyl-1H-indole-3-carbonitrile; 1-Methyl-2-iodoindole-3-carbonitrile; 2-Iodo-1-methylindole-3-carbonitrile; 490039-77-5; 1-Methyl-2-iodo-1H-indole-3-carbonitrile; 2-Iodo-1-methyl-1H-indole-3-carbonitrile; Methyl 2-iodoindole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carbonitrile, 2-Iodo-1-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.