Description

2H-Isoquinolin-1-One CAS NO 489453-23-8 is a high-purity heterocyclic organic compound belonging to the isoquinolinone class, serving as a critical building block in advanced chemical synthesis. Its unique fused-ring structure makes it a valuable intermediate for developing novel pharmaceuticals and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, including charge-transport layers and light-emitting components.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biological studies.
• Academic & Industrial R&D: A versatile starting material for methodological chemistry development and library synthesis in medicinal chemistry programs.
• Dye & Pigment Intermediate: Potential use in synthesizing specialized heterocyclic dyes and colorants.

Basic Information

Product Name	2H-Isoquinolin-1-One
CAS No.	489453-23-8
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	1(2H)-Isoquinolinone; 2H-Isoquinolin-1(2H)-one; Isoquinolin-1(2H)-one; 1-Isoquinolinone; 1,2-Dihydroisoquinolin-1-one; 1-Hydroxyisoquinoline; 1-Oxo-1,2-dihydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2H-Isoquinolin-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.