Description

2-Amino-n-(3-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly for central nervous system and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Biochemical Tool Compound: Utilized in preclinical research to study biological pathways and validate new therapeutic targets.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized heterocyclic compounds.

Basic Information

Product Name	2-Amino-n-(3-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide
CAS No.	489434-80-2
Molecular Formula	C19H23N3OS
Molecular Weight	341.47 g/mol
Synonyms	2-Amino-N-(3-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide; 2-Amino-N-m-tolyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (related fused system); ATC-3-Carboxamide; 489434-80-2; 2-Amino-N-(3-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (common naming variant); Cycloheptathiophene carboxamide derivative; m-Tolyl-substituted aminothiophene carboxamide.
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(3-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.