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(E)-3-(5-Bromothiophen-2-Yl)-n-((2-Methyl-1H-Indol-3-Yl)Methylene)-1H-Pyrazole-5-Carbohydrazide CAS NO 488704-20-7


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CAS No.:488704-20-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(E)-3-(5-Bromothiophen-2-Yl)-n-((2-Methyl-1H-Indol-3-Yl)Methylene)-1H-Pyrazole-5-Carbohydrazide is a high-purity, complex heterocyclic organic compound designed for advanced research and development. This molecule is valued for its unique structural framework, which combines indole, pyrazole, and thiophene moieties, making it a versatile intermediate for synthesizing novel bioactive compounds. It is primarily sought by researchers and development teams in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, chemical biology, and functional material synthesis.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of potential drug candidates, particularly for targeting specific biological pathways.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and hit-to-lead optimization for discovering new therapeutic agents.
  • Agrochemical Development: Acts as a precursor in the design and synthesis of novel pesticides, herbicides, or plant growth regulators.
  • Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function or protein interactions within biological systems.
  • Organic Electronic Materials: Investigated as a potential component in the synthesis of organic semiconductors or light-emitting materials due to its conjugated structure.
  • Academic & Institutional Research: Employed in university and R&D laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name (E)-3-(5-Bromothiophen-2-Yl)-n-((2-Methyl-1H-Indol-3-Yl)Methylene)-1H-Pyrazole-5-Carbohydrazide
CAS No. 488704-20-7
Molecular Formula C₁₈H₁₄BrN₅OS
Molecular Weight 428.31 g/mol
Synonyms 5-Bromo-2-thienyl pyrazole carbohydrazide derivative; (E)-N-((2-Methyl-1H-indol-3-yl)methylene)-3-(5-bromothiophen-2-yl)-1H-pyrazole-5-carbohydrazide; 3-(5-Bromo-2-thienyl)-N-[(2-methyl-1H-indol-3-yl)methylidene]-1H-pyrazole-5-carbohydrazide; 488704-20-7; (E)-3-(5-Bromothiophen-2-yl)-1H-pyrazole-5-carboxylic acid [(2-methyl-1H-indol-3-yl)methylene]hydrazide; Bromothiophene-indole-pyrazole conjugate; BTP carbohydrazide
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Quality Control

Our (E)-3-(5-Bromothiophen-2-Yl)-n-((2-Methyl-1H-Indol-3-Yl)Methylene)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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