Description

(E)-3-(5-Bromothiophen-2-Yl)-n-(3-Methoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide CAS NO 488704-19-4 is a high-purity, heterocyclic organic compound featuring a pyrazole core functionalized with bromothiophene and methoxybenzylidene moieties. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its unique molecular architecture, which is essential for constructing complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the discovery and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry research.
• Organic Synthesis Reagent: Used in advanced organic reactions, including cross-coupling and cyclization, to create complex heterocyclic frameworks.
• Agrochemical Research: Acts as a precursor in the development of new active ingredients for crop protection products.
• Material Science: Investigated for the development of organic electronic materials and functional polymers due to its conjugated structure.
• Academic & Industrial R&D: Employed in universities and corporate labs for method development and exploring new chemical entities.

Basic Information

Product Name	(E)-3-(5-Bromothiophen-2-Yl)-n-(3-Methoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	488704-19-4
Molecular Formula	C₁₆H₁₃BrN₄O₂S
Molecular Weight	405.27 g/mol
Synonyms	(E)-3-(5-Bromothiophen-2-yl)-N-[(3-methoxyphenyl)methylidene]-1H-pyrazole-5-carbohydrazide; (E)-3-(5-Bromothiophen-2-yl)-N-(3-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide; 1H-Pyrazole-5-carbohydrazide, 3-(5-bromo-2-thienyl)-N-[(3-methoxyphenyl)methylene]-; 488704-19-4; (E)-3-(5-Bromothiophen-2-yl)-N-(3-methoxybenzylidene)-1H-pyrazole-5-carboxylic acid hydrazide; 3-(5-Bromothiophen-2-yl)-N-(3-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide
EINECS	Contact for details

Quality Control

Our (E)-3-(5-Bromothiophen-2-Yl)-n-(3-Methoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.