Description

2-(4-Fluorobenzamido)-n-(2-Methoxyethyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with benzothiophene or fluorinated aryl amide pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthetic routes for potential APIs in various therapeutic areas.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme inhibition or receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmaceutical science projects.

Basic Information

Product Name	2-(4-Fluorobenzamido)-n-(2-Methoxyethyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide
CAS No.	488110-24-3
Molecular Formula	C19H21FN2O3S
Molecular Weight	376.45 g/mol
Synonyms	4,5,6,7-Tetrahydro-2-[[(4-fluorophenyl)carbonyl]amino]-N-(2-methoxyethyl)benzo[b]thiophene-3-carboxamide; 2-[(4-Fluorobenzoyl)amino]-N-(2-methoxyethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 488110-24-3; Fluorobenzamido Tetrahydrobenzothiophene Carboxamide; N-(2-Methoxyethyl)-2-[(4-fluorobenzoyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzamido)-n-(2-Methoxyethyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.