Description

1H-Benzimidazole,1-Ethynyl- is a specialized benzimidazole derivative featuring an ethynyl substituent, which serves as a versatile synthetic building block. This compound is valued for its role as a key intermediate in the development of advanced pharmaceutical compounds and functional organic materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or plant growth regulators that leverage the benzimidazole core structure.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, conductive polymers, or advanced coatings.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) due to its terminal alkyne group.
• Bioconjugation: Potential use in labeling biomolecules or creating probe molecules for diagnostic and biochemical research applications.

Basic Information

Product Name	1H-Benzimidazole,1-Ethynyl-
CAS No.	486999-85-3
Molecular Formula	C9H6N2
Molecular Weight	142.16 g/mol
Synonyms	1-Ethynyl-1H-benzimidazole; 1-Ethynylbenzimidazole; 1H-Benzimidazole, 1-ethynyl-; 1-(Ethynyl)benzimidazole; 1-Ethynylbenzimidazole; 1-Ethynyl-1H-benzo[d]imidazole; 1-Ethynylbenzimidazole; 1-Ethynyl-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole,1-Ethynyl- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.