Description

Cyclopropanemethanol, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its stereochemically defined cyclopropane ring fused with a pyridine moiety, which is crucial for imparting specific biological activity and metabolic stability in drug molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular geometry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the cyclopropane structure can enhance compound stability and efficacy.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with novel optical or electronic properties.

Basic Information

Product Name	Cyclopropanemethanol, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	484654-43-5
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	(1R,2R)-2-(Pyridin-3-yl)cyclopropanemethanol; rel-(1R,2R)-2-(3-Pyridinyl)cyclopropanemethanol; (1R,2R)-2-(3-Pyridyl)cyclopropylmethanol; 2-(3-Pyridinyl)cyclopropanemethanol, (1R,2R)-rel-; (1R,2R)-rel-2-(Pyridin-3-yl)cyclopropane-1-methanol; 3-((1R,2R)-2-(Hydroxymethyl)cyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanol, 2-(3-Pyridinyl)-, (1R,2R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.