Description

n-(2,6-Dimethylphenyl)-2-{[4-(4-Methylphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazol-3-Yl]Sulfanyl}Acetamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists exploring novel therapeutic agents, particularly in the areas of kinase inhibition and targeted small molecule drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable supply of complex heterocyclic building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors due to its triazole and pyridine motifs.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) and other high-value fine chemicals.

Basic Information

Product Name	n-(2,6-Dimethylphenyl)-2-{[4-(4-Methylphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazol-3-Yl]Sulfanyl}Acetamide
CAS No.	482640-24-4
Molecular Formula	C24H23N5OS
Molecular Weight	437.54 g/mol
Synonyms	N-(2,6-Dimethylphenyl)-2-{[4-(4-methylphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-({4-(4-Methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl}thio)-N-(2,6-dimethylphenyl)acetamide; 482640-24-4; Acetamide, N-(2,6-dimethylphenyl)-2-[[4-(4-methylphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-; UNII-9J3V4G5U4T; 9J3V4G5U4T; CHEMBL3185141; DTXSID60644669
EINECS	Contact for details

Quality Control

Our n-(2,6-Dimethylphenyl)-2-{[4-(4-Methylphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazol-3-Yl]Sulfanyl}Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.