Description

Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3R,4S,6S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid, polycyclic structure and multiple functional groups make it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those requiring a rigid, three-dimensional scaffold.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of sophisticated ligands for metal-catalyzed asymmetric reactions, enabling high enantioselectivity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, or insecticides where its specific stereochemistry can influence biological activity.
• Material Science Monomer: Potential use in the synthesis of specialty polymers with unique thermal or mechanical properties derived from its bicyclic structure.
• Academic & Industrial R&D: A valuable tool for synthetic chemists exploring new reaction methodologies and constructing complex natural product analogs.

Basic Information

Product Name	Tricyclo[2.2.1.02,6]Heptane-1,3-Dicarboxylic Acid, 3-Amino-, (1R,2R,3R,4S,6S)-
CAS No.	482373-26-2
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	(1R,2R,3R,4S,6S)-3-Aminotricyclo[2.2.1.02,6]heptane-1,3-dicarboxylic acid; 3-Aminobicyclo[2.2.1]heptane-2,5-dicarboxylic acid (stereospecific); endo-3-Aminobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid derivative; Chiral norbornane amino diacid; (1R,2R,3R,4S,6S)-3-Amino-2,5-norbornanedicarboxylic acid; Stereoisomer of 3-Aminotricyclo[2.2.1.02,6]heptane-1,3-dicarboxylic acid; Bicyclic β-amino acid derivative
EINECS	Contact for details

Quality Control

Every batch of this chiral building block is produced and analyzed under strict quality protocols to ensure high chemical and enantiomeric purity, critical for sensitive synthetic applications. Our quality assurance includes comprehensive analytical techniques such as HPLC, chiral chromatography, and NMR to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support development and cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.