Description

2-Thiophenecarboxamide, 5-Chloro-n-[3-[[3-Cyano-4-(3-Oxo-4-Morpholinyl)Phenyl]Amino]-2-Hydroxypropyl]- is a high-purity, complex heterocyclic organic compound with significant potential in advanced pharmaceutical research and development. Its intricate molecular structure, featuring thiophene, morpholinone, and cyano moieties, makes it a valuable pharmacophore and key synthetic intermediate for creating novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzymes or receptors.
• Kinase Inhibitor Research: Used in the discovery and development of kinase inhibitors due to its structural motifs commonly found in such molecules.
• Agrochemical Synthesis: Acts as a precursor in the development of new, high-performance crop protection agents with unique modes of action.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target validation.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Thiophenecarboxamide, 5-Chloro-n-[3-[[3-Cyano-4-(3-Oxo-4-Morpholinyl)Phenyl]Amino]-2-Hydroxypropyl]-
CAS No.	482306-17-2
Molecular Formula	C19H18ClN5O3S
Molecular Weight	431.90 g/mol
Synonyms	5-Chloro-N-[3-({3-cyano-4-(3-oxomorpholin-4-yl)phenyl}amino)-2-hydroxypropyl]thiophene-2-carboxamide; 5-Chloro-N-[3-[[3-cyano-4-(3-oxo-4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-2-thiophenecarboxamide; 482306-17-2; UNII-9F3Z8N8N4I; 9F3Z8N8N4I; CHEMBL3186475; DTXSID60644669; BDBM50111071
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.