Description

Bicyclo[2.2.1]Heptane-2-Carboxaldehyde, 3,3-Dimethyl-, (1R,2R,4S)- (9Ci) is a high-purity, chiral aldehyde derivative of norbornane, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. Its rigid, three-dimensional bicyclic framework and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and the creation of specialty fragrances and flavors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis & Ligand Synthesis: Used as a precursor for developing novel chiral ligands and organocatalysts, enabling enantioselective transformations.
• Agrochemical Development: Serves as a building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Fragrance & Flavor Chemistry: The unique bicyclic structure provides a foundation for synthesizing novel odorants and flavoring agents with complex, long-lasting sensory properties.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored physical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carboxaldehyde, 3,3-Dimethyl-, (1R,2R,4S)- (9Ci)
CAS No.	481660-35-9
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(1R,2R,4S)-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxaldehyde; (1R,2R,4S)-3,3-Dimethyl-2-norbornanecarboxaldehyde; endo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carboxaldehyde (specific isomer); 3,3-Dimethyl-2-norbornanecarboxaldehyde; Chiral Norbornane Aldehyde; 2-Formyl-3,3-dimethylnorbornane
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2-Carboxaldehyde, 3,3-Dimethyl-, (1R,2R,4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analysis, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and production needs with material produced under GMP-like conditions where required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.