Description

1-(Phenylsulfonyl)-6-Indoleboronic Acid is a high-purity, multifunctional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in the development of complex molecules, enabling precise carbon-carbon bond formation. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and materials science.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many active pharmaceutical ingredients (APIs).
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and library synthesis for structure-activity relationship (SAR) studies.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators.
• Materials Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	1-(Phenylsulfonyl)-6-Indoleboronic Acid
CAS No.	480438-52-6
Molecular Formula	C14H12BNO4S
Molecular Weight	301.13 g/mol
Synonyms	6-Borono-1-(phenylsulfonyl)indole; 1-(Benzenesulfonyl)-1H-indol-6-ylboronic acid; 1H-Indole-6-boronic acid, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-1H-indol-6-ylboronic Acid; B-[1-(Phenylsulfonyl)-1H-indol-6-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-6-Indoleboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.