Description

1-tert-Butyl-6-Methyl-3-Bromo-1H-Indole-1,6-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated indole core structure. This compound is critical for enabling precise synthetic pathways in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex indole-based drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Material Science: Acts as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and photoconductive polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	1-tert-Butyl-6-Methyl-3-Bromo-1H-Indole-1,6-Dicarboxylate
CAS No.	479552-81-3
Molecular Formula	C₁₇H₂₀BrNO₄
Molecular Weight	382.25 g/mol
Synonyms	1-tert-Butyl 6-methyl 3-bromo-1H-indole-1,6-dicarboxylate; 3-Bromo-1-(tert-butoxycarbonyl)-6-(methoxycarbonyl)-1H-indole; 1H-Indole-1,6-dicarboxylic acid, 3-bromo-1,6-diethyl ester, 1-(1,1-dimethylethyl) 6-methyl ester; 3-Bromo-1-Boc-6-methyl indole-1,6-dicarboxylate; tert-Butyl 3-bromo-6-(methoxycarbonyl)-1H-indole-1-carboxylate; 479552-81-3; Bromo-indole dicarboxylate derivative
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-6-Methyl-3-Bromo-1H-Indole-1,6-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.