Description

Tolyl 2,3,4-Tri-o-Benzyl-1-Thio-β-D-Glucopyranoside, Thiocresyl 2,3,4-Tri-o-Benzyl-β-D-Glucopyranoside CAS NO 479252-05-6 is a sophisticated, protected thioglycoside building block of significant interest in synthetic organic chemistry. This compound serves as a key glycosyl donor precursor, enabling the controlled synthesis of complex carbohydrate derivatives and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and advanced materials where precise glycosylation is critical.

Application

• Glycochemistry Research: A fundamental building block for the synthesis of complex oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediates: Used in the research and development of glycosidase inhibitors, antiviral agents, and other carbohydrate-based therapeutics.
• Chemical Biology Probes: Serves as a precursor for labeled sugars used in studying carbohydrate-protein interactions and metabolic pathways.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific carbohydrate motifs.
• Process Development: Employed in scaling up glycosylation reactions for commercial pharmaceutical production.
• Academic Synthesis: A valuable reagent for teaching and demonstrating advanced synthetic methodologies in carbohydrate chemistry.

Basic Information

Product Name	Tolyl 2,3,4-Tri-o-Benzyl-1-Thio-β-D-Glucopyranoside, Thiocresyl 2,3,4-Tri-o-Benzyl-β-D-Glucopyranoside
CAS No.	479252-05-6
Molecular Formula	C₃₄H₃₆O₅S
Molecular Weight	556.72 g/mol
Synonyms	Thiocresyl 2,3,4-Tri-O-benzyl-β-D-glucopyranoside; p-Tolyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, 2,3,4-tris-O-(phenylmethyl)-, 1-(4-methylphenyl); 4-Methylphenyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucopyranoside; p-Tolyl 2,3,4-Tri-O-benzyl-1-thio-β-D-glucoside; Protected Thioglucoside Donor; Benzyl-protected thioglucoside.
EINECS	Contact for details

Quality Control

This high-purity synthetic intermediate is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and reliability for sensitive research applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.