Description

(S)-4,5-Dimethyl-2-(Pyrrolidin-2-Yl)Thiazole Hydrobromide is a high-purity chiral thiazole derivative, supplied as its hydrobromide salt for enhanced stability and handling. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block in organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Building block for novel pesticides and herbicides requiring specific stereochemistry for efficacy.
• Fine Chemical Synthesis: Intermediate in the production of specialty chemicals, flavors, and fragrances.
• Academic & Institutional Research: Valuable reagent for methodological development in organic chemistry and chemical biology.

Basic Information

Product Name	(S)-4,5-Dimethyl-2-(Pyrrolidin-2-Yl)Thiazole Hydrobromide
CAS No.	479067-48-6
Molecular Formula	C9H15N2S • HBr
Molecular Weight	263.20 g/mol
Synonyms	(S)-2-(4,5-Dimethylthiazol-2-yl)pyrrolidine hydrobromide; (S)-4,5-Dimethyl-2-(2-pyrrolidinyl)thiazole HBr; L-4,5-Dimethyl-2-(pyrrolidin-2-yl)thiazole hydrobromide; (2S)-2-(4,5-Dimethyl-1,3-thiazol-2-yl)pyrrolidin-1-ium bromide
EINECS	Contact for details

Quality Control

Our production of (S)-4,5-Dimethyl-2-(Pyrrolidin-2-Yl)Thiazole Hydrobromide adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous quality testing, including chiral purity verification, to ensure compliance with research and cGMP-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.