Description

Monobenzyl Phthalate-D4 is a deuterated analog of monobenzyl phthalate, where four hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative analysis in sophisticated mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) workflows. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, environmental testing, and metabolomics sectors, where precise measurement of phthalate esters or related compounds is required.

Application

• Primary use as a stable isotope-labeled internal standard for the quantification of monobenzyl phthalate and related phthalate esters in analytical methods.
• Critical component in LC-MS/MS and GC-MS analysis for pharmaceutical impurity profiling and drug metabolism studies (DMPK).
• Enables high-accuracy trace analysis in environmental monitoring for phthalate contamination in water, soil, and consumer products.
• Supports clinical and forensic toxicology testing for accurate biomarker measurement.
• Used in food safety and packaging migration studies to quantify potential phthalate leachates.
• Facilitates metabolomics research by providing a reference standard for pathway analysis.
• Essential for method development and validation in regulatory-compliant laboratories (e.g., following FDA, EPA guidelines).
• Applied in polymer and material science research to study plasticizer degradation and migration kinetics.

Basic Information

Item	Details
Product Name	Monobenzyl Phthalate-D4
CAS No.	478954-83-5
Molecular Formula	C15H8D4O4
Molecular Weight	260.27 g/mol
Synonyms	Benzyl Hydrogen Phthalate-d4; (Benzyl-d4) Hydrogen Phthalate; Phthalic Acid Monobenzyl-d4 Ester; Monobenzyl-d4 Phthalate; 2-[(2,3,4,5,6-Pentadeuteriobenzyl)oxycarbonyl]benzoic Acid; Deuterated Monobenzyl Phthalate; MBzP-d4; Isotope Labeled MBzP; Internal Standard for Phthalate Analysis
EINECS	Contact for details

Quality Control

Every batch of Monobenzyl Phthalate-D4 is manufactured and analyzed under strict quality systems to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) that detail isotopic enrichment (e.g., D4, atom % D), chemical purity by HPLC, and confirm identity via NMR and MS. Our quality commitment aligns with the standards expected for high-purity reference materials and isotopic standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation and maintain isotopic purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D4)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.