Description

Ethanone, 1-[(1R,4S,6R)-6-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) is a chiral, high-purity bicyclic ketone derivative with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its rigid, functionalized norbornane-like scaffold, which is essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex, stereochemically defined structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its bicyclic framework can contribute to unique biological activity and stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective catalytic processes.
• Material Science: Potential monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties derived from its rigid core.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new synthetic routes in organic chemistry.
• Flavor & Fragrance Intermediate: Can be utilized in the synthesis of complex odorants and flavoring agents with specific stereochemical notes.

Basic Information

Product Name	Ethanone, 1-[(1R,4S,6R)-6-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci)
CAS No.	478943-95-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	rel-(1R,4S,6R)-6-Hydroxybicyclo[2.2.1]heptan-2-yl methyl ketone; 1-[(1R,4S,6R)-6-Hydroxy-2-norbornyl]ethanone; (1R,4S,6R)-6-Acetylbicyclo[2.2.1]heptan-2-ol; Bicyclo[2.2.1]heptan-2-ol, 6-acetyl-, (1R,4S,6R)-rel-; Chiral Hydroxylated Norbornyl Ketone; Advanced Bicyclic Ketone Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purities of ≥97% (by HPLC) and ≥99% enantiomeric excess (by Chiral HPLC), tailored to meet specific project requirements. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent levels are available upon request. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.