Description

4-Methyl-1H-Indazole-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and oncology drug discovery programs. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new molecular entities with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a core scaffold for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for the synthesis of advanced organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-Methyl-1H-Indazole-5-Carboxylic Acid
CAS No.	478837-32-0
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	4-Methyl-1H-indazole-5-carboxylic acid; 5-Carboxy-4-methyl-1H-indazole; 4-Methyl-5-indazolecarboxylic acid; 1H-Indazole-5-carboxylic acid, 4-methyl-; 478837-32-0; 4-Methylindazole-5-carboxylic acid; 4-Methyl-1H-indazol-5-yl carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-1H-Indazole-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.