Description

1H-Indazole, 5-(4-Piperidinyloxy)- is a high-purity, advanced pharmaceutical intermediate with the CAS number 478827-08-6. This compound is valued for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or core structure for constructing compound libraries in high-throughput screening for new drug discovery.
• Kinase Inhibitor Development: Serves as a key structural component in the research and development of novel kinase inhibitors for oncology applications.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme function and receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1H-Indazole, 5-(4-Piperidinyloxy)-
CAS No.	478827-08-6
Molecular Formula	C12H15N3O
Molecular Weight	217.27 g/mol
Synonyms	5-(4-Piperidinyloxy)-1H-indazole; 5-(Piperidin-4-yloxy)-1H-indazole; 4-(1H-Indazol-5-yloxy)piperidine; 5-(Piperidin-4-yloxy)indazole; 1H-Indazol-5-ol, 4-piperidinyl ether; 478827-08-6; 5-Piperidin-4-yloxy-1H-indazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 5-(4-Piperidinyloxy)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.