Description

n-Propyl-3,3,3-D3-Amine Hcl is a deuterium-labeled isotopologue of propylamine hydrochloride, a valuable building block in synthetic organic chemistry. This compound matters for its role as a stable, non-radioactive isotopic tracer, enabling precise metabolic and pharmacokinetic studies. It is primarily needed by pharmaceutical and agrochemical research organizations for use in the synthesis of labeled drug candidates, metabolites, and other bioactive molecules to support drug discovery and development programs.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate for synthesizing isotopically labeled Active Pharmaceutical Ingredients (APIs) and metabolites for Drug Metabolism and Pharmacokinetics (DMPK) studies.
• Analytical Chemistry: Serving as an internal standard in quantitative mass spectrometry (LC-MS, GC-MS) for the accurate bioanalysis of propylamine-containing compounds.
• Mechanistic Studies: Used in isotopic labeling experiments to investigate chemical reaction mechanisms and metabolic pathways.
• Agrochemical Development: Employed in the synthesis of deuterated analogs of pesticides and herbicides to study their environmental fate and degradation.
• Material Science: Potential use in the synthesis of specialty polymers and surface-modifying agents where deuterium labeling is required for analysis.

Basic Information

Product Name	n-Propyl-3,3,3-D3-Amine Hcl
CAS No.	478702-86-2
Molecular Formula	C3H6D3N·HCl
Molecular Weight	99.60 g/mol
Synonyms	1-Aminopropane-3,3,3-d3 hydrochloride; Propylamine-3,3,3-d3 hydrochloride; 3,3,3-Trideuteriopropylamine hydrochloride; n-Propyl-d3-amine HCl; Deuterated Propylamine HCl; Propan-1-amine-3,3,3-d3 hydrochloride; (3,3,3-2H3)Propylamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Propyl-3,3,3-D3-Amine Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.