Description

3-(Furan-2-Carbonyl)-1H-Indole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic indole-furan hybrid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncology Research: Serves as a building block for potential kinase inhibitors and other anti-cancer agents due to its privileged indole structure.
• CNS Drug Development: Employed in the research of compounds targeting neurological disorders, leveraging the bioactivity profile of indole derivatives.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and chemical biology studies.

Basic Information

Product Name	3-(Furan-2-Carbonyl)-1H-Indole-5-Carbonitrile
CAS No.	478677-82-6
Molecular Formula	C₁₄H₈N₂O₂
Molecular Weight	236.23 g/mol
Synonyms	5-Cyano-3-(2-furoyl)-1H-indole; 1H-Indole-5-carbonitrile, 3-(2-furanylcarbonyl)-; 3-(2-Furoyl)-1H-indole-5-carbonitrile; 3-(Furan-2-oyl)-1H-indole-5-carbonitrile; 3-(2-Furancarbonyl)-1H-indole-5-carbonitrile; 5-CN-3-(2-furoyl)indole; Furan-2-yl(5-cyano-1H-indol-3-yl)methanone
EINECS	Contact for details

Quality Control

Our 3-(Furan-2-Carbonyl)-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.